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CA Cancer J Clin (2021) 71:20949

Rotate sites to avoid lipodystrophy

This represents a paradigmatic synergistic crosstalk: acetylation stabilizes and activates a methyltransferase, which in turn reinforces repressive histone methylation to sustain stemness

Caution is needed when combining hydroquinone with other active ingredients like retinoids or glycolic acid, as the combination can cause irritation or increased sensitivity, says Dr