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The simplicity of the protocol is appealing, but the daily commitment and fasting requirement make it more demanding than a once-weekly injection

One aspect of the invention pertains to the administration of one or more NNMT inhibitors by, for example, contacting one or more cells of an animal to: muscular disorders including, but not limited to, sarcopenia, muscle atrophy, Duchenne muscular dystrophy, Becker muscular dystrophy, Limb-girdle muscular dystrophies, Pompe disease, cardiac myopathies, pulmonary disorders

Zhao Y, He A, Zhu F, Ding M, Hao J, Fan Q, Li P, Liu L, Du Y, Liang X, Guo X, Zhang F, Ma X (2018) Integrating genome-wide association study and expression quantitative trait locus study identifies multiple genes and gene sets associated with schizophrenia

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Their health objectives also play an important role