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Nasal and inhaled vaccines also have the potential to induce the formation of transient Bronchus-associated lymphoid tissues (BALT) named inducible BALT (iBALT), in humans and rodents 11,12,13

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11 An ongoing phase I/II clinical trial (NCT 04585750) has assessed the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of PC14586 administration in patients with advanced solid tumors harboring the p53 Y220C mutation