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ACSL4 as a potential target and biomarker for anticancer: From molecular mechanisms to clinical therapeutics

doi: 10.1186/S12888-024-05639-W/TABLES/4 107 ElwoodELimZNaveedHGaleaI

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This iron dependence makes cancer cells more susceptible to ferroptosis ( via inhibited cystine-based reactions ( Focused overview of ferroptosis pathways An overview of ferroptosis pathways is shown in Figure 1

CD38 expression The ability of anti-CD38 antibodies to induce cell death is at least partially dependent on CD38 expression on the MM cell surface