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Region-focused multi-view transformer-based generative adversarial network for cardiac cine MRI reconstruction

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however, for toxicity prediction, cumulative drug exposure, particularly cumulative AUC over the treatment course, appears more informative than isolated peak or trough measurements ( Bayesian forecasting represents a further refinement, combining population pharmacokinetic models with individual patient covariates and measured drug concentrations to generate patient-specific pharmacokinetic parameter estimates and optimize dosing

However, resistance mechanisms arise during the treatment with daratumumab, creating the necessity for new therapies

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