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We are getting a growing number of patients with B12 related symptoms who are not or no longer treated

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The effect of GLP-1 receptor agonists on the exocrine pancreas and the risk of acute pancreatitis has remained a cause for concern

Meanwhile, hypoxia-induced FAO impairment in tubular cells exacerbates lipid accumulation and ferroptosis, while fibrosis itself creates a pathological microenvironmentcompressing renal microvessels to sustain hypoxia and trapping inflammatory cells to perpetuate inflammationthus closing the loop and reinforcing the ferroptosisinflammatoryhypoxicfibrotic cascade

Practitioners should consider specific B 12 dietary counselling for patients currently on a vegetarian, or vegan diet, including patients who have recently initiated such a diet