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In addition, many of these genes have been found to have an immunomodulatory impact on NK cells, by either enabling cancer resistance to NK cell killing, by being critical to NK cell survival and effector responses (Table 2 and Fig

This gap is critical, as metastatic RCC remains incurable with current therapies, and ferroptosis targeting could offer a new avenue to treat advanced disease

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Nuclear factor B signaling and its related non-coding RNAs in cancer therapy

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A previous study by Brown, OCallaghan (142) theoretically suggested that CTLD of Dectin-1 undergo oligomerization and form a quaternary structure when ligand binding to CTLD