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Rating: 4.2214 (20 reviews)

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Description

doi: 10.1007/s00580-014-1907-9 135 OwensS

Department of Energy, 2014)

Urinalyses with careful microscopic examination and renal function tests should be performed during therapy, particularly for those patients with impaired renal function

Furthermore, complicated similarity descriptors are hard to manage by the experimental pharmaceutial chemists and of little use if the scaffold hopping campaign starts from a single active compound only