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We look forward to providing scientific basis and clinical validation for personalized treatment of periodontitis by the mix of multi-center clinical trials and precision medicine in the future

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In osteoarthritis (OA), SHMT2 expression is elevated in chondrocytes, and miR-370 affects the pathological process of osteoarthritis by altering 1C metabolism and DNA methylation through negative regulation of SHMT2 expression [150]

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Hui Shi, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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