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Comparison of recombinant human platelet-derived growth factor-BB plus beta tricalcium phosphate and a collagen membrane to subepithelial connective tissue grafting for the treatment of recession defects: a case series

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Industry Response: The compounding pharmacy industry, medical practitioners, and patient advocacy groups pushed back against the Category 2 classification, arguing that the safety data did not support such a restrictive designation

Clinical symptoms disappeared or improved markedly and rapidly in the vast majority of patients

The presence of the IgG targeting auto-antibody, rheumatoid factor (RF), is also frequently reported in RA patient sera

The majority of studies described above paid attention to homology of the identified gene products with human proteins but ignored the potential impacts of the proposed therapy on the human microbiota