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Advances in the diagnosis and treatment of dry eye

While 12 weeks of bright light exposure did not produce measurable improvements in sleep quality, glucose metabolism, or inflammatory markers, it significantly altered clock gene expression in peripheral blood mononuclear cells (PBMCs, specifically decreasing REV-ERB levels and increasing the REV-ERB/BMAL1 ratio)

doi: 10.1093/jxb/erp048

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Heart rate is the clearest case

Treating obese mice twice a day for a month caused them to gain 10 times less fat than untreated mice and lose 12% of their body weight