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concluded that fenofibrate can inhibit ferroptosis to improve diabetic retinopathy, but did not measure iron-related indices closely associated with ferroptosis, such as iron levels, GPX4, and SLC7A11, indicating that the results require further confirmation [174]

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The primary clinical concern associated with the systemic injection of GHK-Cu is the forced introduction of exogenous copper directly into the bloodstream

However, the addition of exogenous CoQ10 was not found to alleviate ferroptosis in FSP1-deficient cells, indicating that exogenous CoQ10 does not directly affect ferroptosis but rather regulates it indirectly through endogenous CoQ10

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Jin ZG, Berk BC Heart