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Additionally, GSH can react with the NO free radical to produce GSNO, which nitrosylates target proteins

Using attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), researchers observed that cinnamon and chuanxiong oils increased the fluidity and disorder of skin lipids, facilitating percutaneous absorption with enhancement ratios of 2.63 and 2.60, respectivelyvalues exceeding the standard penetration enhancer azone

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This effect was mediated by increasing collagen content and enhancing the body's antioxidant defense mechanisms, specifically through SOD, CAT, and MDA [27]