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As the cells become weaker, they become more vulnerable to damage or apoptosis (cell death) from even small reductions in perfusion, which can occur if the individual becomes dehydrated or overheated, undergoes surgery, has a drop in blood pressure, engages is excess physical activity, has untreated sleep apnea, or experiences a traumatic shock

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However, no significant difference was observed in marble burying behavior between MIA mice and control mice demonstrating 48.9 6.3% buried and 50.2 5.8% buried, respectively

Phielix E, Meex R, Moonen-Kornips E, Hesselink MK, Schrauwen P

doi: 10.1024/0300-9831/a000602 12