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Noteworthy, the association of GLP-1RAs and SGLT-2is is representing a new pharmacological opportunity opening an innovative scenario with potential additive pleiotropic effects that will require further studies

Fold change in DiI-LDL uptake by melanoma PDX cell suspensions treated with heparinases and chondroitinase (1 U/mL of both, dark blue) relative to untreated samples (grey)

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The delivery vectors used in gene therapy, often modified viruses such as adeno-associated viruses (AAVs), have been implicated in cases of immune responses such as haemolytic uraemic syndrome (HUS) (149)

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One of the foremost studied ROS is hydrogen peroxide