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To determine if GSH depletion-induced oxidative stress impairs mitochondrial biogenesis, we used MitoTracker Red to stain live mitochondria

Prophylactic and therapeutic activities in vivo Previous pharmacokinetics studies have revealed that, in humans, co-administration of a 200 mg dose of clofazimine with food results in a C max of 0.41 mg l 1 (equivalent to 0.86 M) at 8 h

[DOI] [PMC free article] [PubMed] [Google Scholar] 206.Pavlov PF

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Extrapulmonary ARDS is typically associated with systemic conditions such as sepsis or trauma that indirectly affect the lungs, whereas intrapulmonary ARDS is caused by direct lung insults like pneumonia or aspiration