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High expression of p49 also inhibited the Sirtuin signal-related mitochondrial repair mechanism, closely related to Sirt3, Sirt4 , and Sirt5 expressions in mitochondria [49]

Correspondingly, engineering of flavonoids pathways in flax plants has shown to increase the accumulation of fatty acids in GM flax seeds and oil (376)

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In particular, the vitamin can reduce the production of prostaglandin E2, which helps to regulate inflammatory pathways [40]

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