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The results convincingly demonstrate that protein aggregation induces senescence of many cell types in the brain, and that senolytics effectively reduce pathogenesis (35-37)

Mean body weight reduction with liraglutide titrated up to 3.0 mg ranged from 2.3 to 12.3 kg, while patients on semaglutide up to 2.4 mg experienced a mean body weight reduction ranging from 8.2 to 15.8 kg

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Tiwary, S

Indeed, as IDD progresses, the disc microenvironment becomes increasingly harsher with severe repercussions on both resident and transplanted cells

The use of sex-mixed cohorts of patients or imbalanced number of women and men during clinical trials also represents a potential source of bias