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Description

Lancet 370 , 511520 (2007)

Int J Cancer 149(7):14951511 Ye Z, Hu Q, Zhuo Q, Zhu Y, Fan G, Liu M et al (2020) Abrogation of ARF6 promotes RSL3-induced ferroptosis and mitigates gemcitabine resistance in pancreatic cancer cells

The viral genome The SARS-CoV-2 genome is a 29.9-kb RNA that consists of 14 open reading frames (ORFs) encoding two large polyproteins (ORF1a and ORF1b) and 13 small ORFs that encode viral structural proteins and other polypeptides

Oxidative stress, viral infection, heat shock, nutrient deprivation, and alkylating agents all lead to activation of the cap-independent translation through IRES thus increasing the amount of Nrf2 [41, 42]