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Stopping treatment may result in gradual return to baseline over months to years

Upregulating SOD3 reduces tumor development and liver metastases in colorectal cancer, indicating that SOD3 may have diagnostic and prognostic implications for the treatment of colorectal cancer [98]

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The phagocytic capacity of macrophages toward ferroptotic tumor cells demonstrates anti-tumor activity, with various immune-stimulatory signals released by ferroptotic tumor cells enhancing phagocytic efficiency ( 6 Iron metabolisms influence on macrophage polarization Macrophages store iron through FT binding, with iron-related gene expression profiles varying across polarization stages

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