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Liver Function Test Abnormalities During Hospitalization Of 461 patients, 122 patients (28.4%) had any kind of LFT abnormalities at admission (including ALT, AST, and GGT)

doi: 10.1016/j.biomaterials.2025.123135 12 FernandezDMGiannarelliC

(A) Representative images of H&E staining, showing histological changes of healthy mice without or with LA 50mg/kg (LA-50) or LA 100mg/kg (LA-100) oral administration

DNA damage caused by oxidative stress can activate ATM/ATR kinases, which in turn activate Chk1/Chk2

Shaker ME., et al

Genetic polymorphisms that alter their activities may therefore change individual exposure to this oxidative metabolite