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doi:10.1016/S0140-6736(21)01751-7 Dutta D, Nagendra L, Harish BG, et al

T., Sonne, N., Andreassen, K

Achieving the weight loss goal would put Novo Nordisk ahead of Eli Lilly by having a weight loss product with the highest efficacy

In all KO genotypes, cFos induction in the AP and NTS was markedly blunted compared to WT mice, establishing that both AMY1R and AMY3R are necessary for transmitting cagrilintides central effects

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Waist circumference reductions were also dose-dependent for Cagrilintide, notably at 1.24.5 mg, exceeding those in the placebo group and approximating the reductions seen with liraglutide 3.0 mg