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Determinants of patient-reported xerostomia among long-term oropharyngeal cancer survivors

Ephraim E and Jewell DE

Numerous cellular processes regulate the sensitivity of cells toward ferroptosis by altering the intracellular labile iron content, and the iron chelator deferoxamine (DFO) can completely inhibit ferroptosis[13, 54, 55]

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Studies have shown that muscle RING-type E3 ubiquitin ligase 1 (MuRF1, TRIM63) and muscle atrophy F-box protein (MaFbx) in the ubiquitinproteasome pathway are closely related to the degradation of muscle protein in cachexia patients [15,16,17]