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FIGURE 10 Oxidative stress, associated with high dose MTX, triggers a systemic inflammatory response where proinflammatory cytokines further contribute to tissue damage (Vanessa Legry et al., 2022), ovariectomized mice (Morsy et al., 2022)

These results suggest that T cells would be involved in the control of gut-microbiota-mediated APAP-ALI rather than exacerbation

Enhanced collagen synthesis in skin models

SQSTM1/p62 promotes the progression of gastric cancer through epithelial-mesenchymal transition

Currently, most of these therapies are still at the cellular and animal levels, and their safety and efficacy on patients have not been conclusively demonstrated