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Description

I dont think it is actually the AI that lowers it directly (I think it is because of lower E2)

Nature 498 , 332337 (2013)

Though it was not that serious

Nevertheless, data from several studies suggest that smoking history should be quantified as a continuous rather than discrete variable, supported by findings such as the likelihood of a lung adenocarcinoma (LUAD) harbouring an EGFR mutation decreasing as number of pack-years increases 10