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2013 Mar;20(3):291-298

Thats a real thing, and its caused by hydrogen peroxide not applied from the outside, but produced from within

Am J Physiol Renal Physiol (2018) 314:F70214

p = 0.002), peroxynitrite (+10.53%

Acknowledgments The gures were created with BioGDP.com ( and CNSFigure ( The authors would like to thank Dr

Beyond the urea cycle, Arg is metabolized by nitric oxide synthase (NOS) to produce NO and citrulline (226), competing with arginase for the same substrate, and activation of arginase reduces NOS-mediated arginine utilization, thereby decreasing NO production (227)