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365,374 A recent study indicated that within 20 years, abnormalities in CSF A 42 , the ratio of CSF A 42 to A 40 , CSF P-tau181, CSF T-tau, CSF neurofilament light chain (NfL), and hippocampal volume (as detected by sMRI) appear in sequence before the clinical diagnosis of SAD

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[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Ku J.W., Gan Y.H