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In contrast, although vacuolar deacidification caused abnormal mitochondria function 33 , the vacuolar degradation of the GFP-tagged mitochondrial matrix protein Idh1 was not increased in the context of V-ATPase-dependent autophagy, suggesting that minimal mitophagy occurred (Supplementary Fig

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Choi SM, Tucker DF, Gross DN, Easton RM, DiPilato LM, Dean AS, Monks BR, Birnbaum MJ

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GH fine-tunes insulin and IGF-I signaling with no impact on IGF-II expression and has a minor impact on fetal development and growth