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In patients that are not stable enough for liver biopsy, such as those with hypotension, coagulopathy or HE, fine-needle aspiration with cytology offers a less-invasive diagnostic approach as it can usually be performed quickly with light sedation

doi: 10.1016/j.ejphar.2020.173198 266 XieSSunWZhangCDongBYangJHouMet al

Versus Alprostadil (Injectable or Urethral ED therapy): Alprostadil is a prostaglandin E1 that can be injected into the penis (Caverject) or inserted as a urethral pellet (MUSE) to cause an erection by locally dilating blood vessels

Mice were randomly assigned to control, 2.0% DSS (model), 2.0% DSS+SAPA (200 mg/kg, positive control), 2.0% DSS + SAC high dose (SAC, 200 g/kg) and 2.0% DSS + SAC low dose (SAC-L, 100 g/kg) groups

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