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Also, in mitochondria from the brain cortex, NO production and NOS expression were decreased [68], and synaptic mitochondrial function was significantly affected [68]

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This response is often coupled with the selective activation of ATF-4 translation, which mediates a protective response including the upregulation of expression of amino acid transporters and de novo synthesis pathways 35,49

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17 reported that SUMOylation-related proteins were expressed in IVD cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Chang L., Geng B., Yu F., Zhao J., Jiang H., Du J., Tang C