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Comparative mechanistic study of RPE cell death induced by different oxidative stresses

It is activated by caspase-1, and it forms pores in the plasma membrane, inducing cell lysis (Tang et al., 2024)

Avornyo, A

Zhang Q, Wang Y, Zhu J, Zou M, Zhang Y, Wu H, et al

Genetic or optogenetic suppression of ROS in these neurons reduces sleep, establishing a bidirectional feedback loop: wakefulness elevates oxidative burden, which triggers sleep, and sleep in turn reduces ROS levels (Kempf et al., 2019)

Working at UCHealth allows me to be part of a large cardiovascular team with multiple sub-specialists to provide cutting edge care, participate in clinical research, and take a collaborative approach to ensure complete care and good outcomes for our patients