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Acknowledgements This work was supported by the National Natural Science Foundation of China (82073313 to D.L.), the joint project of the State Administration of Traditional Chinese Medicine and Health Commission of Shandong Province (GZY-KJS-SD-2023-094), the Traditional Chinese Medicine Special Project of Binzhou Medical University Affiliated Traditional Chinese Medicine Hospital (2023ZYZX02) and the 2023 Qilu Biancang Traditional Chinese Medicine Talent Cultivation Project (to D.L.)

Besides, VDR was found to mediate sperm motility via increasing intracellular calcium concentration [38, 39]

Shane (2023) Which Australian states are banning single-use plastics

In oncology, there's potential for it to target senescent cells within the tumor microenvironment, possibly impeding cancer progression and metastasis

If you learn that you do have significant MTHFR variants that are symptomatic, supplementation with the activated form of folate (vitamin B9) and B12, also known as methyl folate and methylcobalamin respectively, is recommended