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This increase in micronuclei has been observed in both active and inactive RA patients, accompanied by the reduced levels of superoxide dismutase and glutathione peroxidase (49)

There is some evidence that orally administered curcumin accumulates in gastrointestinal tissues

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2 Pharmacological Effects of Berberine 2.1 Oxidative Stress The effect of berberine on a variety of neurodegenerative diseases indicates that it may have a regulatory effect on the common pathways of these diseases

This suggests that disruptions in iron regulation may be linked with developmental anomalies occurring early in the course of schizophrenia (37)