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[2] The bar for FDA drug approval is extremely high, and many compounds that fall short of that bar still have meaningful clinical utility under medical supervision

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Plasma glial fibrillary acidic protein is associated with 18F-SMBT-1 PET: two putative astrocyte reactivity biomarkers for Alzheimers disease

There are also reports of ebselen conjugates with commonly used drugs, such as clioquinol, a compound known for its ability to chelate metal ions and inhibit A deposition