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Studies have identified CYP450 enzymes as a key mechanism through which dietary flavonoids modify the bioavailability of therapeutic drugs

However, the regulatory acceptance of such techniques is critical for their translation from laboratory innovation to routine monitoring systems

Additionally, information regarding their comorbidities and medication is detailed in Table 2

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Anti-tumor angiogenesis increases the normalization of blood vessels, inhibits tumor hypoxia and the immunosuppressive TME, increases the effective drug concentrations in tumors, and enhances drug efficacy

It is indicated that the transfer of specific immunomodulating components, such as bioactive proteins, from mother to infant through human milk contributes to this protective effect