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Common side effects include local reactions at the injection site, hearing and vision impairment, and, less commonly, lung and kidney damage

As a result, inhibiting PHGDH, via RNA interference or pharmacological approaches, is able to hinder the proliferation of cancer cells [14, 73, 74]

The GBS phagocytosis mechanisms vary widely due to 10 known capsular serotypes, and, to our knowledge, no specific mechanisms were reported to each one of these serotypes, as phagocytosis in macrophages strongly differed across clinical GBS isolates, but no correlation was found to capsular serotypes, genetic sequence types, pilus types or clinical sources (Rogers et al., 2018)

Berberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota

In ferroptosis, GSH functions as a cofactor for GPX4 activation to mitigate lipid peroxidation and ROS accumulation, whereas it serves as a copper chaperone to inhibit lipoylated protein aggregation in the TCA cycle in cuproptosis ( GSH, a common biomarker of oxidative stress, may act as the intersection of ferroptosis and cuproptosis during periodontitis ( 3+

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