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Prochzkov et al

The safety profile of topical and oral glutathione seems to be reasonable

NNMT is an enzyme that transfers a methyl group from S-adenosyl-L-methionine to nicotinamide, producing 1-methylnicotinamide and S-adenosyl-L-homocysteine

doi: 10.1016/j.plantsci.2020.110591

Recently, gene therapy has shown promising potential in treating mitochondrial dysfunction and fatty acid metabolic disturbances in HF (Linthout et al., 2024)