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Still, the multifactorial and redundant nature of this phenomenon poses a significant barrier against the identification of effective chemosensitization strategies

Curcumin can cross the blood-brain barrier and has shown to be neuroprotective through upregulating the Nrf2 gene

10.1038/s41598-018-31270-3 Sci

Cd induced disruption of lipid homeostasis in this study is consistent with its characterization as a systematic metabolic disruptor mediated primarily through redox imbalance