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When self-administering the patient should be instructed to [see Dosage and Administration (2.3, 2.4)]: Advise patients that needle breakage has occurred during self-injection of CAVERJECT

Everything below is drawn from the published studies themselves

[DOI] [PubMed] [Google Scholar] Higgins 2002 Higgins JP, Thompson SG

In Vivo Animal Studies : A 2011 study found that this compound's ability to modulate the cell cycle continues at higher concentrations even after its antioxidant effect is saturated, leading researchers to conclude it can interact directly with the cell genome [3]