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Pernicious anemia is an autoimmune disease in which the immune system attacks the parietal cells of the stomach which produce intrinsic factor, a protein normally responsible for most of the bodys B12 absorption

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Interestingly, a deficiency in B12 can affect absorption levels in the gut , which means although you are consuming nutrients, your body is not utilizing it to provide you energy

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This occurs when the bone marrow suddenly starts producing platelets more effectively, along with a rebound effect where platelet production overshoots normal levels

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