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In the supernatants, the concentrations of molecules IL-6, tPA, PAI-1, and vWF were measured with the standard ELISA kits (R&D Systems, Minneapolis, MN, USA)

When inhaled through nebulization, NAC is absorbed directly into the lungs, where it helps break down mucus, neutralize toxins, and promote tissue repair

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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Zhao W, Zhuang P, Chen Y, Wu Y, Zhong M, Lun Y

Considering this, detected the expression levels of autophagy markers (LC3B and PINK1), antioxidative stress markers (SOD1 and GPx1), mitochondrial uncoupling proteins (UCP2, UCP4, and UCP5), and mitochondrial factors including pro-mitochondrial fission factors of dynamin-related protein 1 (DRP1) and its phosphorylated version of p-DRP1, the mitochondrial fission factor (MFF) in charge of pro-midzone-type fission, the mitochondrial fission 1 (FIS1) in charge of pro-peripheral-type fission, and pro-mitochondrial fusion factor mitofusin 2 (MFN2), in SNr and cerebral cortex)