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Another meta-analysis involving a total of 27,823 patients with stage 34 CKD found that SGLT2 inhibitors significantly decreased the risk of primary cardiovascular outcomes, and these benefits were consistent across different levels of kidney function, even in stage 4 CKD [120]

N., Huang, H

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Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinsons disease

All published findings referenced here are based exclusively on animal models and in vitro systems