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Because the nasal dosage forms of vitamin B12 have a lower absorption than intramuscular dosage, nasal dosage forms are administered weekly, rather than the monthly intramuscular dosage

Pre-Treatment Considerations and Risks Patients often ask if they should keep taking B12 before chemo starts

doi: 10.1186/s40104-019-0417-7 4

Potential concerns include unknown long-term safety, product quality variability, and theoretical risks related to angiogenesis and tumor growth

The classical hypothesis suggests that retrograde transport primarily mediates the retrieval of VSRs from multivesicular bodies (MVBs), also referred to as prevacuolar compartments (PVCs), back to the TGN 18,19

Statements Data availability statement The datasets presented in this article are not readily available because of ethical and privacy restrictions