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l-glycine, -sitosterol, phenylpyruvate, and l-serine were up-regulated in the LRC group, while metabolites such as creatinine, dihydrouracil, d-malic acid, and 2-hydroxytyrosol were down-regulated

TIGAR affected the integrity and degradation of mitochondria in 5-8F cells (Feng et al., 2018)

Interventional Clinical Trials: Well-designed trials are urgently needed to evaluate mitoprotective adjuvants (e.g., NMN/NR, elamipretide, metformin) in PLWH

L., et al., Estimated Glomerular Filtration Rate Is a Biomarker of Cognitive Impairment in Parkinson's Disease, Frontiers in Aging Neuroscience 15 (2023): 1130833

[2] In short, it's a vital neutralizer, detoxifier, and protector