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GpoA significantly enhances the bacteriums ability to withstand hostile environments generated by the host immune response, and it also affects in vivo survival, as the gpoA mutant exhibited reduced survival compared to the wild-type strain in various organs of infected mice

Therefore, more efforts need to be made to focus on these issues in future studies on VNS

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Wear loose-fitting underwear, limit prolonged sitting or cycling, avoid saunas and hot tubs, and avoid placing warm objects (such as laptops) on the lap