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Some studies suggest benefits for patients with heart disease, angina, and peripheral artery disease

Causes of low cardiac output in ESRD patients should be thoroughly investigated

doi: 10.1097/00005344-199607000-00023

Pagon RA, Adam MP, Amemiya A, et al

Stroke 23:13121317 Virmani MA, Caso V, Spadoni A, Rossi S, Russo F, Gaetani F (2001) The action of acetyl-l-carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones

Moreover, while high carbohydrate metabolism efficiency was once advantageous, it may now predispose individuals to hyperglycemia when exposed to refined sugars, prevalent in modern diets, further aggravating diabetes risk