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While cuproptosis represents a promising anticancer strategy, its efficacy is limited in solid tumors due to their hypoxic tumor microenvironment (TME) a hallmark feature associated with therapy resistance [39, 206]

Furthermore, the mtDNA nt7778 G-to-T polymorphism does not exacerbate cerulein-induced AP in mice but may accelerate the progression of autoimmune-like lesions after tissue damage, particularly in older mice, indicating its potential role for the polymorphism in autoimmune disease susceptibility following pancreatic injury (157)

Est compuesto por tres aminocidos y desempea un papel clave en la detoxificacin celular, la defensa frente a radicales libres y la regulacin de la melanina

It is the leading cause of severe vision loss in the elderly Caucasian population in the United States

10.1371/journal.pone.0053577 213 Sola-SevillaN.PuertaE

Carbonic Anhydrase Inhibitors These drops decrease fluid production within the eye and may be used alone or in combination with other medications