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Description

For GST pull-down assay, the proteins were purified and GST or GST-TMED10 was incubated with Glutathione agarose (GE, 17-0756-05) (which was blocked by 10% FBS) in IP buffer used for Co-IP, and rotated at 4 C for 1 h

Inherited disorders like Carney complex, neurofibromatosis 2 (NF2), and schwannomatosis lead to schwannomas

Taken together, these data indicate that isoxazole 1 displays high selectivity for Cn Acs1, the enzyme upon which the chemical-genetic screen was designed

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Kim JY, Bae JH, Lee SH, Lee EY, Chung BS, Kim SH, Kang CD

29.95 Prices may be subject to local taxes which are calculated during checkout Similar content being viewed by others Data availability The cryo-EM maps have been deposited into the Electron Microscopy Data Bank under accession numbers EMD-44939 (apo VKGC), EMD-44941 (VKGCTMG2), EMD-44940 (VKGCTMG2 with KH 2 ), EMD-44935 (VKGCFIX with KH 2 ), EMD-44936 (VKGCFX with KH 2 ), EMD-44937 (VKGCPC with KH 2 ) and EMD-44942 (partially carboxylated VKGCFIX with KH 2 )