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Description

Another gut microbial-derived metabolite, capsiate, alleviates ferroptosis induced by intestinal I/R injury by promoting GPX4 expression through the activation of transient receptor potential cation channel subfamily V member 1 [88]

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doi: 10.1016/j.fertnstert.2016.06.005 84 Olivera-ValleILatorreMCCalvoMGasparBGmez-OroCCollazosAet al

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Comparisons between natural agents and standard pharmacological treatments Turmeric (Curcuma longa) vs Clobetasol Propionate : In a randomized-controlled trial, topical 1% turmeric cream showed non-inferior efficacy to 0.05% clobetasol in reducing PASI and pruritus scores over 4 weeks, with fewer adverse events reported in the turmeric group, indicating better tolerability (Guevara et al

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Insulin-like Growth Factor 1 (IGF-1) is one of the most powerful growth mediators in the human body

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Studies reveal that phosphatidylethanolamine (PE)-bound PUFAs, particularly PE-AA and PE-AdA, exhibit marked sensitivity to ferroptosis ( 2.2 GPX4 and its role in suppressing ferroptosis in melanoma ROS, which include hydrogen peroxide (H 2 O 2 ), hydroxyl radicals (OH), singlet oxygen ( 1 O 2 ), and superoxide (O 2 ), among others ( 10 ) mediated electron transfer, approximately 1%2% of electrons leak during their transport from Complex I and II to Complex III (Gutierrez-Mariscal et al., 2021)

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