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In women, low cortisol helps reignite the estrogen and progesterone interplay required for ovulation and implantation

Statistical analysis Differences between measured values (mean SD, n = 6) were detected by one-way analysis of variance (ANOVA), accompanied by the TukeyKramer multiple comparison test aided with GraphPad Prism 5 software

doi: 10.15252/embj.201899430 151 BhatiaDChungKPNakahiraKPatinoERiceMCTorresLKet al

Low levels of potentially toxic oxygen metabolites are physiologically generated in cells and tissues during oxidative phosphorylation.10 The resulting moderate levels of ROS play an integral role in the modulation of several physiological functions of the cell, including gene expression, signal transduction, and defense against invading pathogens